Refine your search
Collections
Journals
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Rawat, Pooja
- A Method for Synthesis of Gold Nanoparticles Using 1-Amino-2-Naphthol-4-Sulphonic Acid as Reducing Agent
Abstract Views :240 |
PDF Views:90
Authors
Affiliations
1 Animal Biochemistry Division, ICAR-National Dairy Research Institute, Karnal 132 001, IN
2 Dairy Chemistry Division, ICAR-National Dairy Research Institute, Karnal 132 001, IN
1 Animal Biochemistry Division, ICAR-National Dairy Research Institute, Karnal 132 001, IN
2 Dairy Chemistry Division, ICAR-National Dairy Research Institute, Karnal 132 001, IN
Source
Current Science, Vol 110, No 12 (2016), Pagination: 2297-2300Abstract
The present communication describes the synthesis of gold nanoparticles (AuNPs) using 1-amino-2- naphthol-4-sulphonic acid (ANSA) with enhanced stability. The method of preparation is similar to the conventional method using sodium citrate as reducing agent. Briefly, ANSA was quickly added to a boiled solution of hydrogen tetrachloroaurate under stirring, resulting in the synthesis of deep red-coloured AuNPs. The AuNPs prepared by ANSA (AuNPs-ANSA) exhibit twofold increase in stability towards sodium chloride over those prepared by sodium citrate. AuNPs-ANSA are 35.1 nm in size and particles has various shapes, viz. hexagonal, pentagonal, spherical, etc. AuNPs-ANSA can be functionalized with immunoglobulins and functionalized nanoparticles exhibit flow properties in lateral-flow assay.Keywords
Gold Nanoparticles, Immunoglobulins, Lateral Flow Assay, Reducing Agent.- Challenges in the Promotion of Herbals as Alternative and Complementary Medicine
Abstract Views :246 |
PDF Views:76
Authors
Affiliations
1 Value Addition Research and Development – Human Health, National Innovation Foundation-India, Grambharti, Mahudi Road, Gandhinagar 382 650, IN
1 Value Addition Research and Development – Human Health, National Innovation Foundation-India, Grambharti, Mahudi Road, Gandhinagar 382 650, IN
Source
Current Science, Vol 115, No 10 (2018), Pagination: 1837-1838Abstract
Herbals, particularly traditional herbal medicines (codified or non-codified) are of immense value. These have significantly contributed to the development of various medications, and hence have become the focus area of researchers for drug discovery. Eighty per cent of the medications of plant origin are suggested to be based on original ethnopharmacological uses1. Paclitaxel (Taxol®), the most extensively used drug for breast cancer, was isolated from Taxus brevifolia bark. Artemisinin and its derivative artemotil, isolated from Artemisia annua and quinine, isolated from Cinchona succirubra bark are approved antimalarial drugs. Apomorphine, used to treat Parkinson’s disease, is a derivative of morphine, which was isolated from Papaver somniferum. Many more effective and safe herbals may be developed as alternative and complementary medicine for different indications with inclusive efforts of the governments, policy makers and technocrats.References
- Dias, D. A., Urban, S. and Roessner, U., Metabolites, 2012, 2, 303–336.
- Dang, H., Wang, Q., Wang, H., Yan, M. and Liu, X., Phytother. Res., 2016, 30, 292–297.
- Liberti, L. E. and Der Marderosian, A., J. Pharm. Sci., 1978, 67, 1487–1489.
- Sangwan, R. S. et al., Curr. Sci., 2004, 86, 461–465.
- Wurglics, M. et al., J. Am. Pharm. Assoc., 2001, 41, 560–566.
- Schlag, E. M. and McIntosh, M. S., Phytochemistry, 2006, 67, 1510–1519.
- Andola, H. C., Rawal, R. S., Rawat, M. S. M., Bhatt, I. D. and Purohit, V. K., Asian J. Biotechnol., 2010, 2, 239– 245.
- Rieger, G., Müller, M., Guttenberger, H. and Bucar, F., J. Agric. Food Chem., 2008, 56, 9080–9086.
- Ma, M., Hong, C. L., An, S. Q. and Li, B., J. Agric. Food Chem., 2003, 51, 2390–2393.
- Cartea, M. E., Velasco, P., Obregón, S., Padilla, G. and de Haro, A., Phytochemistry, 2008, 69, 403–410.
- Salminen, J. P., Ossipov, V., Haukioja, E. and Pihlaja, K., Phytochemistry, 2001, 57, 15–22.
- Southwell, I. A. and Bourke, C. A., Phytochemistry, 2001, 56, 437–441.
- Patel, P., Int. J. Res. Ayurveda Pharm., 2011, 2, 1148–1154.
- Ernst, E., J. Int. Med., 2002, 252, 107– 113.
- Park, H. J. et al., J. Forensic Sci., 2016, 61, 226–229.
- Ko, R. J., N. Engl. J. Med., 1998, 339, 847.
- Fugh-Berman, A., Lancet, 2000, 355, 134–138.
- Oga, E. F., Sekine, S., Shitara, Y. and Horie, T., Eur. J. Drug Metab. Pharmacokinet., 2016, 41, 93–108.
- Bansal, G., Suthar, N., Kaur, J. and Jain, A., Phytother. Res., 2016, 30, 1046– 1058.
- Bhatt, A., Perspect. Clin. Res., 2016, 7, 59–61.